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1 article(s) from Strazewski, Peter

Towards the preparation of synthetic outer membrane vesicle models with micromolar affinity to wheat germ agglutinin using a dialkyl thioglycoside

Dimitri Fayolle,
Nathalie Berthet,
Bastien Doumeche,
Olivier Renaudet,
Peter Strazewski and
Michele Fiore

Beilstein J. Org. Chem. 2019, 15, 937–946, doi:10.3762/bjoc.15.90

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Figure 1: Structure of the β-thiols 1a and 1b and of the commercial alkenes 2a and 2b.

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Scheme 1: Synthesis of the n-alkyl thioglycosides 3–5, 7 and 8. Detailed reaction conditions are reported in ...

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Scheme 2: Synthesis of the lipophilic scaffold 6; DMAP = N,N-dimethylaminopyridine.

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Figure 2: Periodic monitoring by ¹H NMR (300 MHz, DMF-d₇) of the formation of product 8 from a mixture compou...

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Figure 3: Micrographs of giant vesicles and lipid aggregates obtained from the gentle hydration (in PBS, pH 7...

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Figure 4: A simplified (and not in scale) representation of the ELLA assay, to study the interaction between ...

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Figure 5: Inhibition curves for the binding of WGA-HRP to PAA-GlcNAc by D-GlcNAc The symbols (■), ( [Graphic 2] ) and (○) ...

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Figure 6: Main poses obtained from docking experiments. WGA (PDB 2UVO) surface is shown in white for monomer ...

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Published 17 Apr 2019

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